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» On the correlation of binary sequences
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BMCBI
2008
144views more  BMCBI 2008»
14 years 10 months ago
Pep-3D-Search: a method for B-cell epitope prediction based on mimotope analysis
Background: The prediction of conformational B-cell epitopes is one of the most important goals in immunoinformatics. The solution to this problem, even if approximate, would help...
Yanxin Huang, Yongli Bao, Shu Yan Guo, Yan Wang, C...
BMCBI
2008
123views more  BMCBI 2008»
14 years 10 months ago
Validation of protein models by a neural network approach
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...
BMCBI
2008
138views more  BMCBI 2008»
14 years 10 months ago
Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote ho
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Inkyung Jung, Jaehyung Lee, Soo-Young Lee, Dongsup...
BMCBI
2006
88views more  BMCBI 2006»
14 years 10 months ago
Protein kinases associated with the yeast phosphoproteome
Background: Protein phosphorylation is an extremely important mechanism of cellular regulation. A large-scale study of phosphoproteins in a whole-cell lysate of Saccharomyces cere...
Ross I. Brinkworth, Alan L. Munn, Bostjan Kobe
BMCBI
2006
108views more  BMCBI 2006»
14 years 10 months ago
Gene function classification using Bayesian models with hierarchy-based priors
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
Babak Shahbaba, Radford M. Neal