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» On the correlation of binary sequences
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BMCBI
2010
138views more  BMCBI 2010»
15 years 21 days ago
Sigma-2: Multiple sequence alignment of non-coding DNA via an evolutionary model
Background: While most multiple sequence alignment programs expect that all or most of their input is known to be homologous, and penalise insertions and deletions, this is not a ...
Gayathri Jayaraman, Rahul Siddharthan
BMCBI
2011
14 years 4 months ago
HomPPI: A Class of Sequence Homology Based Protein-Protein Interface Prediction Methods
Background: Although homology-based methods are among the most widely used methods for predicting the structure and function of proteins, the question as to whether interface sequ...
Li C. Xue, Drena Dobbs, Vasant Honavar
NIPS
1996
15 years 1 months ago
Continuous Sigmoidal Belief Networks Trained using Slice Sampling
Real-valued random hidden variables can be useful for modelling latent structure that explains correlations among observed variables. I propose a simple unit that adds zero-mean G...
Brendan J. Frey
78
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BMCBI
2007
113views more  BMCBI 2007»
15 years 21 days ago
Hinge Atlas: relating protein sequence to sites of structural flexibility
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
Samuel Flores, Long J. Lu, Julie Yang, Nicholas Ca...
97
Voted
BMCBI
2006
127views more  BMCBI 2006»
15 years 19 days ago
Automatic discovery of cross-family sequence features associated with protein function
Background: Methods for predicting protein function directly from amino acid sequences are useful tools in the study of uncharacterised protein families and in comparative genomic...
Markus Brameier, Josien Haan, Andrea Krings, Rober...