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» On the correlation of binary sequences
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90
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BMCBI
2010
134views more  BMCBI 2010»
15 years 21 days ago
Localizing triplet periodicity in DNA and cDNA sequences
Background: The protein-coding regions (coding exons) of a DNA sequence exhibit a triplet periodicity (TP) due to fact that coding exons contain a series of three nucleotide codon...
Liya Wang, Lincoln D. Stein
109
Voted
BMCBI
2005
150views more  BMCBI 2005»
15 years 14 days ago
Discover protein sequence signatures from protein-protein interaction data
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...
BMCBI
2011
14 years 7 months ago
Flexible taxonomic assignment of ambiguous sequencing reads
Background: To characterize the diversity of bacterial populations in metagenomic studies, sequencing reads need to be accurately assigned to taxonomic units in a given reference ...
José Carlos Clemente, Jesper Jansson, Gabri...
BIBE
2007
IEEE
167views Bioinformatics» more  BIBE 2007»
15 years 4 months ago
Assessing the Performance of Macromolecular Sequence Classifiers
Machine learning approaches offer some of the most cost-effective approaches to building predictive models (e.g., classifiers) in a broad range of applications in computational bio...
Cornelia Caragea, Jivko Sinapov, Vasant Honavar, D...
112
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BMCBI
2006
152views more  BMCBI 2006»
15 years 19 days ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...