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BMCBI
2008
111views more  BMCBI 2008»
14 years 10 months ago
SimHap GUI: An intuitive graphical user interface for genetic association analysis
Background: Researchers wishing to conduct genetic association analysis involving single nucleotide polymorphisms (SNPs) or haplotypes are often confronted with the lack of user-f...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer
BMCBI
2007
153views more  BMCBI 2007»
14 years 10 months ago
Can Clustal-style progressive pairwise alignment of multiple sequences be used in RNA secondary structure prediction?
Background: In ribonucleic acid (RNA) molecules whose function depends on their final, folded three-dimensional shape (such as those in ribosomes or spliceosome complexes), the se...
Amelia B. Bellamy-Royds, Marcel Turcotte
BMCBI
2007
128views more  BMCBI 2007»
14 years 10 months ago
A Bayesian nonparametric method for prediction in EST analysis
Background: Expressed sequence tags (ESTs) analyses are a fundamental tool for gene identification in organisms. Given a preliminary EST sample from a certain library, several sta...
Antonio Lijoi, Ramsés H. Mena, Igor Prü...
BMCBI
2010
108views more  BMCBI 2010»
14 years 10 months ago
An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs
Background: Transcription factors (TFs) control transcription by binding to specific regions of DNA called transcription factor binding sites (TFBSs). The identification of TFBSs ...
Fernando Garcia-Alcalde, Armando Blanco, Adrian J....
BMCBI
2010
153views more  BMCBI 2010»
14 years 10 months ago
Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering
Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
Eva Freyhult, Mattias Landfors, Jenny Önskog,...
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