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BMCBI
2006
207views more  BMCBI 2006»
13 years 6 months ago
A new measure for functional similarity of gene products based on Gene Ontology
Background: Gene Ontology (GO) is a standard vocabulary of functional terms and allows for coherent annotation of gene products. These annotations provide a basis for new methods ...
Andreas Schlicker, Francisco S. Domingues, Jö...
BMCBI
2010
142views more  BMCBI 2010»
13 years 6 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan
ECCB
2008
IEEE
14 years 22 days ago
Functional coherence in domain interaction networks
Motivation: Extracting functional information from protein–protein interactions (PPI) poses significant challenges arising from the noisy, incomplete, generic and static nature...
Jayesh Pandey, Mehmet Koyutürk, Shankar Subra...
NAR
2008
115views more  NAR 2008»
13 years 6 months ago
Data growth and its impact on the SCOP database: new developments
The Structural Classification of Proteins (SCOP) database is a comprehensive ordering of all proteins of known structure, according to their evolutionary and structural relationsh...
Antonina Andreeva, Dave Howorth, John-Marc Chandon...
CSB
2003
IEEE
176views Bioinformatics» more  CSB 2003»
13 years 11 months ago
3D Structural Homology Detection via Unassigned Residual Dipolar Couplings
Recognition of a protein’s fold provides valuable information about its function. While many sequence-based homology prediction methods exist, an important challenge remains: tw...
Christopher James Langmead, Bruce Randall Donald