2542 search results - page 472 / 509 » One step ahead |
BMCBI
2010
14 years 9 months ago
2010
Background: A widely used method to find conserved secondary structure in RNA is to first construct a multiple sequence alignment, and then fold the alignment, optimizing a score ...
BMCBI
2010
14 years 9 months ago
2010
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
111
click to vote
BMCBI
2010
14 years 9 months ago
2010
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
BMCBI
2010
14 years 9 months ago
2010
Background: The estimation of demographic parameters from genetic data often requires the computation of likelihoods. However, the likelihood function is computationally intractab...
BMCBI
2010
14 years 9 months ago
2010
Background: To understand an RNA sequence's mechanism of action, the structure must be known. Furthermore, target RNA structure is an important consideration in the design of...