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» Ontology-Based Interactive Information Extraction
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GECCO
2010
Springer
191views Optimization» more  GECCO 2010»
15 years 5 months ago
Initialization parameter sweep in ATHENA: optimizing neural networks for detecting gene-gene interactions in the presence of sma
Recent advances in genotyping technology have led to the generation of an enormous quantity of genetic data. Traditional methods of statistical analysis have proved insufficient i...
Emily Rose Holzinger, Carrie C. Buchanan, Scott M....
116
Voted
KDD
2008
ACM
138views Data Mining» more  KDD 2008»
16 years 29 days ago
A visual-analytic toolkit for dynamic interaction graphs
In this article we describe a visual-analytic tool for the interrogation of evolving interaction network data such as those found in social, bibliometric, WWW and biological appli...
Xintian Yang, Sitaram Asur, Srinivasan Parthasarat...
130
Voted
BMCBI
2010
136views more  BMCBI 2010»
15 years 21 days ago
A hub-attachment based method to detect functional modules from confidence-scored protein interactions and expression profiles
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
Chia-Hao Chin, Shu-Hwa Chen, Chin-Wen Ho, Ming-Tat...
ECCB
2008
IEEE
15 years 7 months ago
Functional coherence in domain interaction networks
Motivation: Extracting functional information from protein–protein interactions (PPI) poses significant challenges arising from the noisy, incomplete, generic and static nature...
Jayesh Pandey, Mehmet Koyutürk, Shankar Subra...
93
Voted
BMCBI
2008
82views more  BMCBI 2008»
15 years 20 days ago
Envelope: interactive software for modeling and fitting complex isotope distributions
Background: An important aspect of proteomic mass spectrometry involves quantifying and interpreting the isotope distributions arising from mixtures of macromolecules with differe...
Michael T. Sykes, James R. Williamson