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119
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: Virtual or in silico ligand screening combined with other computational methods is one of the most promising methods to search for new lead compounds, thereby greatly ...
121
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: Transposable elements are abundant in eukaryotic genomes and it is believed that they have a significant impact on the evolution of gene and chromosome structure. Whil...
114
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BMCBI
2010
15 years 3 months ago
2010
Background: The enormous throughput and low cost of second-generation sequencing platforms now allow research and clinical geneticists to routinely perform single experiments that...
114
Voted
BMCBI
2008
2008
RPPAML/RIMS: A metadata format and an information management system for reverse phase protein arrays
15 years 3 months ago
Background: Reverse Phase Protein Arrays (RPPA) are convenient assay platforms to investigate the presence of biomarkers in tissue lysates. As with other high-throughput technolog...
123
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BMCBI
2006
15 years 3 months ago
2006
Background: Single nucleotide polymorphisms (SNPs) as defined here are single base sequence changes or short insertion/deletions between or within individuals of a given species. ...