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    BMCBI
    2006
    172views more  BMCBI 2006»
    BioWarehouse: a bioinformatics database warehouse toolkit
    14 years 9 months ago
    BioWarehouse: a bioinformatics database warehouse toolkit
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    Background: This article addresses the problem of interoperation of heterogeneous bioinformatics databases. Results: We introduce BioWarehouse, an open source toolkit for construc...
    Thomas J. Lee, Yannick Pouliot, Valerie Wagner, Pr...
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    BMCBI
    2006
    92views more  BMCBI 2006»
    Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
    14 years 9 months ago
    Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
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    Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
    Bradford C. Powell, Clyde A. Hutchison III
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    BMCBI
    2006
    111views more  BMCBI 2006»
    Using ESTs to improve the accuracy of de novo gene prediction
    14 years 9 months ago
    Using ESTs to improve the accuracy of de novo gene prediction
    Download  mblab.wustl.edu
    Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
    Chaochun Wei, Michael R. Brent
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    BMCBI
    2006
    108views more  BMCBI 2006»
    Gene function classification using Bayesian models with hierarchy-based priors
    14 years 9 months ago
    Gene function classification using Bayesian models with hierarchy-based priors
    Download  www.cs.utoronto.ca
    We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
    Babak Shahbaba, Radford M. Neal
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    BMCBI
    2006
    113views more  BMCBI 2006»
    QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyp
    14 years 9 months ago
    QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyp
    Download  www.biomedcentral.com
    Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
    Jifeng Tang, Ben Vosman, Roeland E. Voorrips, C. G...
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