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141
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BMCBI
2006
15 years 3 months ago
2006
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
166
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BMCBI
2006
15 years 3 months ago
2006
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
139
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BMCBI
2006
15 years 3 months ago
2006
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
157
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BMCBI
2006
15 years 3 months ago
2006
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
126
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BMCBI
2006
15 years 3 months ago
2006
Background: Expressed sequence tag (EST) analyses provide a rapid and economical means to identify candidate genes that may be involved in a particular biological process. These E...