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BMCBI
2007
181views more  BMCBI 2007»
14 years 11 months ago
ASMPKS: an analysis system for modular polyketide synthases
Background: Polyketides are secondary metabolites of microorganisms with diverse biological activities, including pharmacological functions such as antibiotic, antitumor and agroc...
Hongseok Tae, Eun-Bae Kong, Kiejung Park
104
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BMCBI
2004
208views more  BMCBI 2004»
14 years 11 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
SADM
2010
196views more  SADM 2010»
14 years 6 months ago
Bayesian adaptive nearest neighbor
: The k nearest neighbor classification (k-NN) is a very simple and popular method for classification. However, it suffers from a major drawback, it assumes constant local class po...
Ruixin Guo, Sounak Chakraborty
PR
2008
113views more  PR 2008»
14 years 11 months ago
Do unbalanced data have a negative effect on LDA?
For two-class discrimination, Ref. [1] claimed that, when covariance matrices of the two classes were unequal, a (class) unbalanced dataset had a negative effect on the performanc...
Jing-Hao Xue, D. Mike Titterington
SEMCO
2007
IEEE
15 years 5 months ago
Unrestricted Coreference: Identifying Entities and Events in OntoNotes
Most research in the field of anaphora or coreference detection has been limited to noun phrase coreference, usually on a restricted set of entities, such as ACE entities. In par...
Sameer S. Pradhan, Lance A. Ramshaw, Ralph M. Weis...