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103
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BMCBI
2007
14 years 12 months ago
2007
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
95
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BMCBI
2007
14 years 12 months ago
2007
Background: Identity by descent (IBD) matrix estimation is a central component in mapping of Quantitative Trait Loci (QTL) using variance component models. A large number of algor...
90
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BMCBI
2008
14 years 12 months ago
2008
Background: The principles of protein folding and evolution pose problems of very high inherent complexity. Often these problems are tackled using simplified protein models, e.g. ...
BMCBI
2008
14 years 12 months ago
2008
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
CN
2008
14 years 12 months ago
2008
Electrical-to-optical domain conversions and vice versa (denoted by O/E/O conversions) for each hop in optical core transport networks impose considerable capital and financial ov...