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170
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AI
2008
Springer
15 years 25 days ago
Expressive probabilistic description logics
The work in this paper is directed towards sophisticated formalisms for reasoning under probabilistic uncertainty in ontologies in the Semantic Web. Ontologies play a central role...
Thomas Lukasiewicz
BMCBI
2010
154views more  BMCBI 2010»
15 years 24 days ago
Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data
Background: A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine which DNA-b...
Robert C. McLeay, Timothy L. Bailey
97
Voted
BMCBI
2010
193views more  BMCBI 2010»
15 years 24 days ago
Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
Background: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-...
Jakub Mieczkowski, Magdalena E. Tyburczy, Michal D...
94
Voted
BMCBI
2010
111views more  BMCBI 2010»
15 years 24 days ago
Dynamic probe selection for studying microbial transcriptome with high-density genomic tiling microarrays
Background: Current commercial high-density oligonucleotide microarrays can hold millions of probe spots on a single microscopic glass slide and are ideal for studying the transcr...
Hedda Høvik, Tsute Chen
119
Voted
BMCBI
2010
151views more  BMCBI 2010»
15 years 24 days ago
Misty Mountain clustering: application to fast unsupervised flow cytometry gating
Background: There are many important clustering questions in computational biology for which no satisfactory method exists. Automated clustering algorithms, when applied to large,...
István P. Sugár, Stuart C. Sealfon