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» Optimization Multiple Sequence Alignment Scheme in DC-BTA
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RECOMB
2009
Springer
15 years 10 months ago
Learning Models for Aligning Protein Sequences with Predicted Secondary Structure
Accurately aligning distant protein sequences is notoriously difficult. A recent approach to improving alignment accuracy is to use additional information such as predicted seconda...
Eagu Kim, Travis J. Wheeler, John D. Kececioglu
BMCBI
2010
118views more  BMCBI 2010»
14 years 9 months ago
Towards realistic benchmarks for multiple alignments of non-coding sequences
Background: With the continued development of new computational tools for multiple sequence alignment, it is necessary today to develop benchmarks that aid the selection of the mo...
Jaebum Kim, Saurabh Sinha
BIBM
2007
IEEE
132views Bioinformatics» more  BIBM 2007»
15 years 4 months ago
A Divide-and-Conquer Implementation of Three Sequence Alignment and Ancestor Inference
In this paper, we present an algorithm to simultaneously align three biological sequences with affine gap model and infer their common ancestral sequence. Our algorithm can be fu...
Feng Yue, Jijun Tang
RECOMB
2012
Springer
13 years 4 hour ago
Estimating the Accuracy of Multiple Alignments and its Use in Parameter Advising
We develop a novel and general approach to estimating the accuracy of protein multiple sequence alignments without knowledge of a reference alignment, and use our approach to addre...
Dan F. DeBlasio, Travis J. Wheeler, John D. Kececi...
BMCBI
2007
126views more  BMCBI 2007»
14 years 9 months ago
Multiple non-collinear TF-map alignments of promoter regions
Background: The analysis of the promoter sequence of genes with similar expression patterns is a basic tool to annotate common regulatory elements. Multiple sequence alignments ar...
Enrique Blanco, Roderic Guigó, Xavier Messe...