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» Optimization Multiple Sequence Alignment Scheme in DC-BTA
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CPM
2004
Springer
156views Combinatorics» more  CPM 2004»
15 years 3 months ago
A Computational Model for RNA Multiple Structural Alignment.
Abstract. This paper addresses the problem of aligning multiple sequences of non-coding RNA genes. We approach this problem with the biologically motivated paradigm that scoring of...
Eugene Davydov, Serafim Batzoglou
BMCBI
2007
147views more  BMCBI 2007»
14 years 9 months ago
MaxAlign: maximizing usable data in an alignment
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
Rodrigo Gouveia-Oliveira, Peter Wad Sackett, Ander...
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BMCBI
2010
154views more  BMCBI 2010»
14 years 9 months ago
Fine-tuning structural RNA alignments in the twilight zone
Background: A widely used method to find conserved secondary structure in RNA is to first construct a multiple sequence alignment, and then fold the alignment, optimizing a score ...
Andreas Bremges, Stefanie Schirmer, Robert Giegeri...
WABI
2005
Springer
120views Bioinformatics» more  WABI 2005»
15 years 3 months ago
Multiple Structural RNA Alignment with Lagrangian Relaxation
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Markus Bauer, Gunnar W. Klau, Knut Reinert
COMPLIFE
2005
Springer
15 years 3 months ago
Fast and Accurate Structural RNA Alignment by Progressive Lagrangian Optimization
During the last few years new functionalities of RNA have been discovered, renewing the need for computational tools for their analysis. To this respect, multiple sequence alignmen...
Markus Bauer, Gunnar W. Klau, Knut Reinert