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» Optimization Multiple Sequence Alignment Scheme in DC-BTA
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BMCBI
2006
121views more  BMCBI 2006»
14 years 9 months ago
Evaluation of sequence alignments and oligonucleotide probes with respect to three-dimensional structure of ribosomal RNA using
Background: Availability of high-resolution RNA crystal structures for the 30S and 50S ribosomal subunits and the subsequent validation of comparative secondary structure models h...
Yadhu Kumar, Ralf Westram, Peter Kipfer, Harald Me...
CSB
2003
IEEE
128views Bioinformatics» more  CSB 2003»
15 years 2 months ago
Degenerate Primer Design via Clustering
This paper describes a new strategy for designing degenerate primers for a given multiple alignment of amino acid sequences. Degenerate primers are useful for amplifying homologou...
Xintao Wei, David N. Kuhn, Giri Narasimhan
BMCBI
2007
130views more  BMCBI 2007»
14 years 9 months ago
HMM-ModE - Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying e
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
Prashant K. Srivastava, Dhwani K. Desai, Soumyadee...
BMCBI
2008
211views more  BMCBI 2008»
14 years 9 months ago
CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment
Background: Searching for similarities in protein and DNA databases has become a routine procedure in Molecular Biology. The Smith-Waterman algorithm has been available for more t...
Svetlin Manavski, Giorgio Valle
ICC
2009
IEEE
135views Communications» more  ICC 2009»
15 years 4 months ago
Block Detection of Multiple Symbol DPSK in a Statistically Unknown Time-Varying Channel
—We present a detection scheme for multiple-symbol DPSK for use in a statistically unknown time-varying channel. The scheme relies on a parametric representation of the timevaryi...
Nathan Ricklin, James R. Zeidler