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» Optimization Multiple Sequence Alignment Scheme in DC-BTA
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GECCO
2006
Springer
171views Optimization» more  GECCO 2006»
15 years 1 months ago
A hybrid genetic search for multiple sequence alignment
This paper proposes a hybrid genetic algorithm for multiple sequence alignment. The algorithm evolves guide sequences and aligns input sequences based on the guide sequences. It a...
Seung-Hyun Moon, Sung-Soon Choi, Byung Ro Moon
80
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IPPS
2006
IEEE
15 years 3 months ago
Parallel multiple sequence alignment with local phylogeny search by simulated annealing
The problem of multiple sequence alignment is one of the most important problems in computational biology. In this paper we present a new method that simultaneously performs multi...
Jaroslaw Zola, Denis Trystram, Andrei Tchernykh, C...
KELSI
2004
Springer
15 years 3 months ago
A Randomized Algorithm for Distance Matrix Calculations in Multiple Sequence Alignment
Multiple sequence alignment (MSA) is a vital problem in biology. Optimal alignment of multiple sequences becomes impractical even for a modest number of sequences [1] since the gen...
Sanguthevar Rajasekaran, Vishal Thapar, Hardik Dav...
CPM
1998
Springer
115views Combinatorics» more  CPM 1998»
15 years 1 months ago
Aligning Alignments
d abstract) John Kececioglu and Dean Starrett Department of Computer Science The University of Arizona Tucson AZ 85721, USA A basic computational problem that arises in both the...
John D. Kececioglu, Weiqing Zhang
BMCBI
2004
141views more  BMCBI 2004»
14 years 9 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin