12 search results - page 2 / 3 » Optimization in Discovery of Compound Granules |
BMCBI
2008
14 years 10 months ago
2008
Background: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new the...
CIBCB
2007
IEEE
15 years 4 days ago
2007
IEEE
—In metabolic engineering it is difficult to identify which set of genetic manipulations will result in a microbial strain that achieves a desired production goal, due to the co...
100
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IDEAL
2004
Springer
15 years 3 months ago
2004
Springer
Proteins are known to perform a biological function by interacting with other proteins or compounds. Since protein–protein interaction is intrinsic to most cellular processes, pr...
103
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ISMB
2000
14 years 11 months ago
2000
Several microarray technologies that monitor the level of expression of a large number of genes have recently emerged. Given DNA-microarray data for a set of cells characterized b...
115
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BMCBI
2008
14 years 10 months ago
2008
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...