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BMCBI
2007
93views more  BMCBI 2007»
14 years 9 months ago
SVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...
IPM
2008
100views more  IPM 2008»
14 years 9 months ago
Query-level loss functions for information retrieval
Many machine learning technologies such as support vector machines, boosting, and neural networks have been applied to the ranking problem in information retrieval. However, since...
Tao Qin, Xu-Dong Zhang, Ming-Feng Tsai, De-Sheng W...
JMLR
2006
132views more  JMLR 2006»
14 years 9 months ago
Learning to Detect and Classify Malicious Executables in the Wild
We describe the use of machine learning and data mining to detect and classify malicious executables as they appear in the wild. We gathered 1,971 benign and 1,651 malicious execu...
Jeremy Z. Kolter, Marcus A. Maloof
BMCBI
2004
140views more  BMCBI 2004»
14 years 9 months ago
What can we learn from noncoding regions of similarity between genomes?
Background: In addition to known protein-coding genes, large amounts of apparently non-coding sequence are conserved between the human and mouse genomes. It seems reasonable to as...
Thomas A. Down, Tim J. P. Hubbard
BMCBI
2004
123views more  BMCBI 2004»
14 years 9 months ago
Interaction profile-based protein classification of death domain
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
Drew Lett, Michael Hsing, Frederic Pio