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114
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BMCBI
2010
111views more  BMCBI 2010»
15 years 3 months ago
Dynamic probe selection for studying microbial transcriptome with high-density genomic tiling microarrays
Background: Current commercial high-density oligonucleotide microarrays can hold millions of probe spots on a single microscopic glass slide and are ideal for studying the transcr...
Hedda Høvik, Tsute Chen
133
Voted
BMCBI
2010
115views more  BMCBI 2010»
15 years 3 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
109
Voted
BMCBI
2010
86views more  BMCBI 2010»
15 years 3 months ago
An automatic method for identifying surface proteins in bacteria: SLEP
Background: Bacterial infections represent a global health challenge. The identification of novel antibacterial targets for both therapy and vaccination is needed on a constant ba...
Emanuela Giombini, Massimiliano Orsini, Danilo Car...
121
Voted
BMCBI
2010
110views more  BMCBI 2010»
15 years 3 months ago
OLS Dialog: An open-source front end to the Ontology Lookup Service
Background: With the growing amount of biomedical data available in public databases it has become increasingly important to annotate data in a consistent way in order to allow ea...
Harald Barsnes, Richard G. Côté, Ingv...
119
Voted
BMCBI
2010
92views more  BMCBI 2010»
15 years 3 months ago
YODA: Software to facilitate high-throughput analysis of chronological life span, growth rate, and survival in budding yeast
Background: The budding yeast Saccharomyces cerevisiae is one of the most widely studied model organisms in aging-related science. Although several genetic modifiers of yeast long...
Brady Olsen, Christopher J. Murakami, Matt Kaeberl...
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