Sciweavers

34170 search results - page 6633 / 6834
» Optimization
Sort
View
117
Voted
BMCBI
2008
105views more  BMCBI 2008»
15 years 3 months ago
Using the longest significance run to estimate region-specific p-values in genetic association mapping studies
Background: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increas...
Ie-Bin Lian, Yi-Hsien Lin, Ying-Chao Lin, Hsin-Cho...
132
Voted
BMCBI
2007
146views more  BMCBI 2007»
15 years 3 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
125
Voted
BMCBI
2008
105views more  BMCBI 2008»
15 years 3 months ago
Novel computational methods for increasing PCR primer design effectiveness in directed sequencing
Background: Polymerase chain reaction (PCR) is used in directed sequencing for the discovery of novel polymorphisms. As the first step in PCR directed sequencing, effective PCR pr...
Kelvin Li, Anushka Brownley, Timothy B. Stockwell,...
132
Voted
BMCBI
2008
133views more  BMCBI 2008»
15 years 3 months ago
MS-DOCK: Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening
Background: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new the...
Nicolas Sauton, David Lagorce, Bruno O. Villoutrei...
128
Voted
BMCBI
2008
108views more  BMCBI 2008»
15 years 3 months ago
Signature Evaluation Tool (SET): a Java-based tool to evaluate and visualize the sample discrimination abilities of gene express
Background: The identification of specific gene expression signature for distinguishing sample groups is a dominant field in cancer research. Although a number of tools have been ...
Chih-Hung Jen, Tsun-Po Yang, Chien-Yi Tung, Shu-Ha...
« Prev « First page 6633 / 6834 Last » Next »