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134
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BMCBI
2006
100views more  BMCBI 2006»
15 years 3 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight
149
Voted
BMCBI
2006
153views more  BMCBI 2006»
15 years 3 months ago
Automatic document classification of biological literature
Background: Document classification is a wide-spread problem with many applications, from organizing search engine snippets to spam filtering. We previously described Textpresso, ...
David Chen, Hans-Michael Müller, Paul W. Ster...
114
Voted
BMCBI
2006
60views more  BMCBI 2006»
15 years 3 months ago
Use of a multi-way method to analyze the amino acid composition of a conserved group of orthologous proteins in prokaryotes
Background: Amino acids in proteins are not used equally. Some of the differences in the amino acid composition of proteins are between species (mainly due to nucleotide compositi...
Alberto Pasamontes, Santiago Garcia-Vallvé
117
Voted
BMCBI
2006
136views more  BMCBI 2006»
15 years 3 months ago
Java GUI for InterProScan (JIPS): A tool to help process multiple InterProScans and perform ortholog analysis
Background: Recent, rapid growth in the quantity of available genomic data has generated many protein sequences that are not yet biochemically classified. Thus, the prediction of ...
Aijazuddin Syed, Chris Upton
111
Voted
BMCBI
2006
97views more  BMCBI 2006»
15 years 3 months ago
Selecting normalization genes for small diagnostic microarrays
Background: Normalization of gene expression microarrays carrying thousands of genes is based on assumptions that do not hold for diagnostic microarrays carrying only few genes. T...
Jochen Jaeger, Rainer Spang
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