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BMCBI
2005
87views more  BMCBI 2005»
15 years 3 months ago
ProfNet, a method to derive profile-profile alignment scoring functions that improves the alignments of distantly related protei
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
Tomas Ohlson, Arne Elofsson
BMCBI
2005
79views more  BMCBI 2005»
15 years 3 months ago
Mathematical design of prokaryotic clone-based microarrays
Background: Clone-based microarrays, on which each spot represents a random genomic fragment, are a good alternative to open reading frame-based microarrays, especially for microo...
Bart Pieterse, Elisabeth J. Quirijns, Frank H. J. ...
137
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BMCBI
2005
109views more  BMCBI 2005»
15 years 3 months ago
Automation of gene assignments to metabolic pathways using high-throughput expression data
Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...
Liviu Popescu, Golan Yona
154
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TJS
2008
105views more  TJS 2008»
15 years 3 months ago
Using a relational database for scalable XML search
XML is a flexible and powerful tool that enables information and security sharing in heterogeneous environments. Scalable technologies are needed to effectively manage the growing...
Rebecca Cathey, Steven M. Beitzel, Eric C. Jensen,...
BMCBI
2005
105views more  BMCBI 2005»
15 years 3 months ago
SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management
Background: Single nucleotide polymorphisms (SNPs) provide an important tool in pinpointing susceptibility genes for complex diseases and in unveiling human molecular evolution. S...
Lin Wang, Simin Liu, Tianhua Niu, Xin Xu
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