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BMCBI
2011
14 years 4 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
DAC
2004
ACM
15 years 1 months ago
A methodology to improve timing yield in the presence of process variations
The ability to control the variations in IC fabrication process is rapidly diminishing as feature sizes continue towards the sub-100 nm regime. As a result, there is an increasing...
Sreeja Raj, Sarma B. K. Vrudhula, Janet Meiling Wa...
ALMOB
2007
151views more  ALMOB 2007»
14 years 9 months ago
Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...
Stefan Wolfsheimer, Bernd Burghardt, Alexander K. ...
WSC
2000
14 years 11 months ago
Analyzing transformation-based simulation metamodels
We present a technique for analyzing a simulation metamodel that has been constructed using a variancestabilizing transformation. To compute a valid confidence interval for the ex...
Maria de los A. Irizarry, Michael E. Kuhl, Emily K...
CIKM
2009
Springer
15 years 4 months ago
A social recommendation framework based on multi-scale continuous conditional random fields
This paper addresses the issue of social recommendation based on collaborative filtering (CF) algorithms. Social recommendation emphasizes utilizing various attributes informatio...
Xin Xin, Irwin King, Hongbo Deng, Michael R. Lyu