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BMCBI
2010
161views more  BMCBI 2010»
14 years 12 months ago
BPDA - A Bayesian peptide detection algorithm for mass spectrometry
Background: Mass spectrometry (MS) is an essential analytical tool in proteomics. Many existing algorithms for peptide detection are based on isotope template matching and usually...
Youting Sun, Jianqiu Zhang, Ulisses Braga-Neto, Ed...
BMCBI
2008
90views more  BMCBI 2008»
14 years 12 months ago
Function2Gene: A gene selection tool to increase the power of genetic association studies by utilizing public databases and expe
Background: Many common disorders have multiple genetic components which convey increased susceptibility. SNPs have been used to identify genetic components which are associated w...
Don L. Armstrong, Chaim O. Jacob, Raphael Zidovetz...
BMCBI
2008
96views more  BMCBI 2008»
14 years 12 months ago
Novel methodology for construction and pruning of quasi-median networks
Background: Visualising the evolutionary history of a set of sequences is a challenge for molecular phylogenetics. One approach is to use undirected graphs, such as median network...
Sarah C. Ayling, Terence A. Brown
BMCBI
2007
105views more  BMCBI 2007»
14 years 12 months ago
Predicting RNA secondary structure by the comparative approach: how to select the homologous sequences
Background: The secondary structure of an RNA must be known before the relationship between its structure and function can be determined. One way to predict the secondary structur...
Stefan Engelen, Fariza Tahi
BMCBI
2007
151views more  BMCBI 2007»
14 years 12 months ago
Minimus: a fast, lightweight genome assembler
Background: Genome assemblers have grown very large and complex in response to the need for algorithms to handle the challenges of large whole-genome sequencing projects. Many of ...
Daniel D. Sommer, Arthur L. Delcher, Steven L. Sal...
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