68 search results - page 13 / 14 » Over-optimism in bioinformatics: an illustration |
BMCBI
2008
13 years 6 months ago
2008
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
BMCBI
2007
13 years 6 months ago
2007
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
BMCBI
2008
13 years 6 months ago
2008
Background: Modelling the time-related behaviour of biological systems is essential for understanding their dynamic responses to perturbations. In metabolic profiling studies, the...
BMCBI
2008
13 years 6 months ago
2008
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
BMCBI
2008
13 years 6 months ago
2008
Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...