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BMCBI
2005
292views more  BMCBI 2005»
15 years 4 months ago
Atlas - a data warehouse for integrative bioinformatics
Background: We present a biological data warehouse called Atlas that locally stores and integrates biological sequences, molecular interactions, homology information, functional a...
Sohrab P. Shah, Yong Huang, Tao Xu, Macaire M. S. ...
BMCBI
2005
152views more  BMCBI 2005»
15 years 4 months ago
Ranking the whole MEDLINE database according to a large training set using text indexing
Background: The MEDLINE database contains over 12 million references to scientific literature, ut 3/4 of recent articles including an abstract of the publication. Retrieval of ent...
Brian P. Suomela, Miguel A. Andrade
BMCBI
2005
86views more  BMCBI 2005»
15 years 4 months ago
Chromosomal clustering of a human transcriptome reveals regulatory background
Background: There has been much evidence recently for a link between transcriptional regulation and chromosomal gene order, but the relationship between genomic organization, regu...
Jan H. Vogel, Anja von Heydebreck, Antje Purmann, ...
BMCBI
2005
94views more  BMCBI 2005»
15 years 4 months ago
A method for finding single-nucleotide polymorphisms with allele frequencies in sequences of deep coverage
Background: The allele frequencies of single-nucleotide polymorphisms (SNPs) are needed to select an optimal subset of common SNPs for use in association studies. Sequence-based m...
Jianmin Wang, Xiaoqiu Huang
BMCBI
2005
97views more  BMCBI 2005»
15 years 4 months ago
Comparative mapping of sequence-based and structure-based protein domains
Background: Protein domains have long been an ill-defined concept in biology. They are generally described as autonomous folding units with evolutionary and functional independenc...
Ya Zhang, John-Marc Chandonia, Chris H. Q. Ding, S...
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