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BMCBI
2010
127views more  BMCBI 2010»
14 years 9 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
JCC
2011
154views more  JCC 2011»
14 years 16 days ago
Can we trust docking results? Evaluation of seven commonly used programs on PDBbind database
: Docking is one of the most commonly used techniques in drug design. It is used for both identifying correct poses of a ligand in the binding site of a protein as well as for the ...
Dariusz Plewczynski, Michal Lazniewski, Rafal Augu...
BIBE
2006
IEEE
112views Bioinformatics» more  BIBE 2006»
15 years 3 months ago
Finding Correlations in Functionally Equivalent Proteins by Integrating Automated and Visual Data Exploration
The analysis of alignments of functionally equivalent proteins can reveal regularities such as correlated positions or residue patterns which are important to ensure a specific f...
Daniel A. Keim, Daniela Oelke, Royal Truman, Klaus...
95
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BMCBI
2008
163views more  BMCBI 2008»
14 years 9 months ago
ProfileGrids as a new visual representation of large multiple sequence alignments: a case study of the RecA protein family
Background: Multiple sequence alignments are a fundamental tool for the comparative analysis of proteins and nucleic acids. However, large data sets are no longer manageable for v...
Alberto I. Roca, Albert E. Almada, Aaron C. Abajia...
57
Voted
RECOMB
2008
Springer
15 years 10 months ago
Bootstrapping the Interactome: Unsupervised Identification of Protein Complexes in Yeast
Protein interactions and complexes are major components of biological systems. Recent genome-wide applications of tandem affinity purification (TAP) in yeast have increased signifi...
Caroline C. Friedel, Jan Krumsiek, Ralf Zimmer