I propose a set of criteria which distinguish a grand challenge in science or engineering from the many other kinds of short-term or long-term research problems that engage the int...
One approach to high-performance processing of massive data sets is to incorporate computation into storage systems. Previous work has shown that this active storage model is effe...
Rajiv Wickremesinghe, Jeffrey S. Chase, Jeffrey Sc...
The problem of multiple sequence alignment is one of the most important problems in computational biology. In this paper we present a new method that simultaneously performs multi...
Jaroslaw Zola, Denis Trystram, Andrei Tchernykh, C...
This paper investigates the design of parallel algorithmic strategies that address the efficient use of both, memory hierarchies within each processor and a multilevel clustered ...
Frank K. H. A. Dehne, Stefano Mardegan, Andrea Pie...
Public computing can potentially supply not only computational power but also memory and short term storage resources to grid and cluster scale problems. Gene sequence alignment i...