Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Rapid development of DNA sequencing technologies exponentially increases the amount of publicly available genomic data. Whole genome multiple sequence alignments represent a parti...
Pavol Hanus, Janis Dingel, Georg Chalkidis, Joachi...
d abstract) John Kececioglu and Dean Starrett Department of Computer Science The University of Arizona Tucson AZ 85721, USA A basic computational problem that arises in both the...
We develop a novel and general approach to estimating the accuracy of protein multiple sequence alignments without knowledge of a reference alignment, and use our approach to addre...
Dan F. DeBlasio, Travis J. Wheeler, John D. Kececi...
A common task in biological research is to predict function for proteins by comparing sequences between proteins of known and unknown function. This is often done using pair-wise ...