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EVOW
2010
Springer
15 years 3 months ago
Improving Multi-Relief for Detecting Specificity Residues from Multiple Sequence Alignments
A challenging problem in bioinformatics is the detection of residues that account for protein function specificity, not only in order to gain deeper insight in the nature of functi...
Elena Marchiori
BMCBI
2008
176views more  BMCBI 2008»
14 years 12 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
BMCBI
2004
96views more  BMCBI 2004»
14 years 11 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
ICPADS
2005
IEEE
15 years 5 months ago
A Parallel Implementation of 2-D/3-D Image Registration for Computer-Assisted Surgery
: Image registration is a technique usually used for aligning two different images taken at different times and/or from different viewing points. A key challenge for medical image ...
Fumihiko Ino, Yasuhiro Kawasaki, Takahito Tashiro,...
RECOMB
2005
Springer
16 years 1 days ago
Using Multiple Alignments to Improve Gene Prediction
The multiple species de novo gene prediction problem can be stated as follows: given an alignment of genomic sequences from two or more organisms, predict the location and structur...
Samuel S. Gross, Michael R. Brent