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BMCBI
2008
202views more  BMCBI 2008»
14 years 10 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2008
102views more  BMCBI 2008»
14 years 10 months ago
Fast splice site detection using information content and feature reduction
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...
A. K. M. A. Baten, Saman K. Halgamuge, Bill C. H. ...
BMCBI
2006
120views more  BMCBI 2006»
14 years 10 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu
BMCBI
2006
121views more  BMCBI 2006»
14 years 10 months ago
Splice site identification using probabilistic parameters and SVM classification
Background: Recent advances and automation in DNA sequencing technology has created a vast amount of DNA sequence data. This increasing growth of sequence data demands better and ...
A. K. M. A. Baten, Bill C. H. Chang, Saman K. Halg...
JMLR
2002
137views more  JMLR 2002»
14 years 9 months ago
The Subspace Information Criterion for Infinite Dimensional Hypothesis Spaces
A central problem in learning is selection of an appropriate model. This is typically done by estimating the unknown generalization errors of a set of models to be selected from a...
Masashi Sugiyama, Klaus-Robert Müller