Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Background: The detection of relationships between a protein sequence of unknown function and a sequence whose function has been characterised enables the transfer of functional a...
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
Protein function prediction is an active area of research in bioinformatics. And yet, transfer of annotation on the basis of sequence or structural similarity remains widely used ...
Protein fold recognition is the prediction of protein’s tertiary structure (Fold) given the protein’s sequence without relying on sequence similarity. Using machine learning t...