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BMCBI
2010
96views more  BMCBI 2010»
14 years 10 months ago
A statistical framework for differential network analysis from microarray data
Background: It has been long well known that genes do not act alone; rather groups of genes act in consort during a biological process. Consequently, the expression levels of gene...
Ryan Gill, Somnath Datta, Susmita Datta
BMCBI
2008
129views more  BMCBI 2008»
14 years 10 months ago
A unified approach to false discovery rate estimation
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
Korbinian Strimmer
BMCBI
2007
102views more  BMCBI 2007»
14 years 10 months ago
Setting up a large set of protein-ligand PDB complexes for the development and validation of knowledge-based docking algorithms
Background: The number of algorithms available to predict ligand-protein interactions is large and ever-increasing. The number of test cases used to validate these methods is usua...
Luis A. Diago, Persy Morell, Longendri Aguilera, E...
INTR
2007
81views more  INTR 2007»
14 years 9 months ago
Network externality and future usage of Internet services
Purpose – The purpose of this paper is to investigate different effects of three network externality factors, i.e. local network size, network strength, and total network size, ...
Sung Yong Chun, Minhi Hahn
BMCBI
2005
141views more  BMCBI 2005»
14 years 9 months ago
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
Nils E. Magnusson, Alessandra K. Cardozo, Mogens K...