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BMCBI
2010
181views more  BMCBI 2010»
14 years 12 months ago
Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...
Amit Zeisel, Amnon Amir, Wolfgang J. Köstler,...
TVCG
2008
124views more  TVCG 2008»
14 years 11 months ago
Effective visualization of complex vascular structures using a non-parametric vessel detection method
The effective visualization of vascular structures is critical for diagnosis, surgical planning as well as treatment evaluation. In recent work, we have developed an algorithm for ...
Alark Joshi, Xiaoning Qian, Donald P. Dione, Ketan...
RECOMB
2003
Springer
16 years 4 days ago
Accurate detection of very sparse sequence motifs
Protein sequence alignments are more reliable the shorter the evolutionary distance. Here, we align distantly related proteins using many closely spaced intermediate sequences as ...
Andreas Heger, Michael Lappe, Liisa Holm
PLDI
2010
ACM
15 years 4 months ago
Detecting Inefficiently-Used Containers to Avoid Bloat
Runtime bloat degrades significantly the performance and scalability of software systems. An important source of bloat is the inefficient use of containers. It is expensive to cre...
Guoqing Xu, Atanas Rountev
BMCBI
2010
89views more  BMCBI 2010»
14 years 12 months ago
Detection of gene pathways with predictive power for breast cancer prognosis
Background: Prognosis is of critical interest in breast cancer research. Biomedical studies suggest that genomic measurements may have independent predictive power for prognosis. ...
Shuangge Ma, Michael R. Kosorok