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BMCBI
2008
137views more  BMCBI 2008»
14 years 12 months ago
A dynamic Bayesian network approach to protein secondary structure prediction
Background: Protein secondary structure prediction method based on probabilistic models such as hidden Markov model (HMM) appeals to many because it provides meaningful informatio...
Xin-Qiu Yao, Huaiqiu Zhu, Zhen-Su She
BMCBI
2007
108views more  BMCBI 2007»
14 years 12 months ago
Publishing perishing? Towards tomorrow's information architecture
Scientific articles are tailored to present information in human-readable aliquots. Although the Internet has revolutionized the way our society thinks about information, the trad...
Michael R. Seringhaus, Mark B. Gerstein
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BMCBI
2008
114views more  BMCBI 2008»
14 years 12 months ago
Indel PDB: A database of structural insertions and deletions derived from sequence alignments of closely related proteins
Background: Insertions and deletions (indels) represent a common type of sequence variations, which are less studied and pose many important biological questions. Recent research ...
Michael Hsing, Artem Cherkasov
BMCBI
2008
158views more  BMCBI 2008»
14 years 12 months ago
Metrics for GO based protein semantic similarity: a systematic evaluation
Background: Several semantic similarity measures have been applied to gene products annotated with Gene Ontology terms, providing a basis for their functional comparison. However,...
Catia Pesquita, Daniel Faria, Hugo P. Bastos, Ant&...
BMCBI
2008
135views more  BMCBI 2008»
14 years 12 months ago
Facilitating the development of controlled vocabularies for metabolomics technologies with text mining
Background: Many bioinformatics applications rely on controlled vocabularies or ontologies to consistently interpret and seamlessly integrate information scattered across public r...
Irena Spasic, Daniel Schober, Susanna-Assunta Sans...