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ISMDA
2004
Springer
15 years 3 months ago
Model Selection and Adaptation for Biochemical Pathways
In bioinformatics, biochemical signal pathways can be modeled by many differential equations. It is still an open problem how to fit the huge amount of parameters of the equations...
Rüdiger W. Brause
PSB
2004
14 years 11 months ago
An Evidence Ontology for Use in Pathway/Genome Databases
An important emerging need in Model Organism Databases (MODs) and other bioinformatics databases (DBs) is that of capturing the scientific evidence that supports the information wi...
Peter D. Karp, Suzanne M. Paley, Cynthia J. Kriege...
WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
15 years 4 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka
CSB
2004
IEEE
154views Bioinformatics» more  CSB 2004»
15 years 1 months ago
Multi-Knockout Genetic Network Analysis: The Rad6 Example
A novel and rigorous Multi-perturbation Shapley Value Analysis (MSA) method has been recently presented [12]. The method addresses the challenge of defining and calculating the fu...
Alon Kaufman, Martin Kupiec, Eytan Ruppin
BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
14 years 10 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...