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CSB
2005
IEEE
128views Bioinformatics» more  CSB 2005»
14 years 12 months ago
Application of a Generalized MWC Model for the Mathematical Simulation of Metabolic Pathways Regulated by Allosteric Enzymes
In our effort to elucidate the systems biology of the model organism, Escherichia coli, we have developed a mathematical model that simulates the allosteric regulation for threoni...
Tarek S. Najdi, Chin-Rang Yang, Bruce E. Shapiro, ...
CSB
2004
IEEE
126views Bioinformatics» more  CSB 2004»
15 years 1 months ago
Boosted PRIM with Application to Searching for Oncogenic Pathway of Lung Cancer
Boosted PRIM (Patient Rule Induction Method) is a new algorithm developed for two-class classification problems. PRIM is a variation of those Tree-Based methods ( [4] Ch9.3), seek...
Pei Wang, Young Kim, Jonathan R. Pollack, Robert T...
ISCIS
2009
Springer
15 years 4 months ago
A web-based data source for metabolomics
—With the development of improved and cost-effective technologies, it is now possible to detect thousands of metabolites in biofluids or specific organs, and reliably quantify th...
Ali Cakmak, Arun Dsouza, Richard Hanson, Gultekin ...
BIODATAMINING
2008
140views more  BIODATAMINING 2008»
14 years 10 months ago
Modeling gene-by-environment interaction in comorbid depression with alcohol use disorders via an integrated bioinformatics appr
Background: Comorbidity of Major Depressive Disorder (depression) and Alcohol Use Disorders (AUD) is well documented. Depression, AUD, and the comorbidity of depression with AUD s...
Richard C. McEachin, Benjamin J. Keller, Erika F. ...
WABI
2007
Springer
15 years 4 months ago
Bringing Folding Pathways into Strand Pairing Prediction
Abstract. The topology of β-sheets is defined by the pattern of hydrogenbonded strand pairing. Therefore, predicting hydrogen bonded strand partners is a fundamental step towards...
Jieun K. Jeong, Piotr Berman, Teresa M. Przytycka