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» Pathway Logic: Executable Models of Biological Networks
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BMCBI
2006
129views more  BMCBI 2006»
14 years 11 months ago
Functional clustering of yeast proteins from the protein-protein interaction network
Background: The abundant data available for protein interaction networks have not yet been fully understood. New types of analyses are needed to reveal organizational principles o...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
CSB
2005
IEEE
189views Bioinformatics» more  CSB 2005»
15 years 5 months ago
Learning Yeast Gene Functions from Heterogeneous Sources of Data Using Hybrid Weighted Bayesian Networks
We developed a machine learning system for determining gene functions from heterogeneous sources of data sets using a Weighted Naive Bayesian Network (WNB). The knowledge of gene ...
Xutao Deng, Huimin Geng, Hesham H. Ali
ATVA
2008
Springer
131views Hardware» more  ATVA 2008»
15 years 1 months ago
Computation Tree Regular Logic for Genetic Regulatory Networks
Model checking has proven to be a useful analysis technique not only for concurrent systems, but also for the genetic regulatory networks (Grns) that govern the functioning of livi...
Radu Mateescu, Pedro T. Monteiro, Estelle Dumas, H...
EVOW
2009
Springer
14 years 9 months ago
Evolutionary Approaches for Strain Optimization Using Dynamic Models under a Metabolic Engineering Perspective
One of the purposes of Systems Biology is the quantitative modeling of biochemical networks. In this effort, the use of dynamical mathematical models provides for powerful tools in...
Pedro Evangelista, Isabel Rocha, Eugénio C....
107
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AB
2007
Springer
15 years 5 months ago
Relating Attractors and Singular Steady States in the Logical Analysis of Bioregulatory Networks
Abstract. In 1973 R. Thomas introduced a logical approach to modeling and analysis of bioregulatory networks. Given a set of Boolean functions describing the regulatory interaction...
Heike Siebert, Alexander Bockmayr