Sciweavers

183 search results - page 4 / 37
» Pathway Logic: Executable Models of Biological Networks
Sort
View
CMSB
2009
Springer
15 years 6 months ago
Probabilistic Approximations of Signaling Pathway Dynamics
Systems of ordinary differential equations (ODEs) are often used to model the dynamics of complex biological pathways. We construct a discrete state model as a probabilistic appro...
Bing Liu, P. S. Thiagarajan, David Hsu
WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
15 years 6 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka
BIBE
2008
IEEE
111views Bioinformatics» more  BIBE 2008»
15 years 1 months ago
Structure learning for biomolecular pathways containing cycles
Bayesian network structure learning is a useful tool for elucidation of regulatory structures of biomolecular pathways. The approach however is limited by its acyclicity constraint...
S. Itani, Karen Sachs, Garry P. Nolan, M. A. Dahle...
RECOMB
2006
Springer
15 years 12 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
80
Voted
BMCBI
2008
117views more  BMCBI 2008»
14 years 11 months ago
Using a logical model to predict the growth of yeast
Background: A logical model of the known metabolic processes in S. cerevisiae was constructed from iFF708, an existing Flux Balance Analysis (FBA) model, and augmented with inform...
Ken E. Whelan, Ross D. King