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» Pathway Logic: Executable Models of Biological Networks
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BIRTHDAY
2010
Springer
14 years 9 months ago
Some Thoughts on the Semantics of Biocharts
Abstract. This paper combines three topics to which Amir Pnueli contributed significantly: the semantics of languages for concurrency, the semantics of statecharts, and reactive an...
David Harel, Hillel Kugler
IJBRA
2006
59views more  IJBRA 2006»
14 years 11 months ago
Predicting altered pathways using extendable scaffolds
: Many diseases, especially solid tumors, involve the disruption or deregulation of cellular processes. Most current work using gene expression and other high-throughput data, simp...
B. M. Broom, T. J. McDonnell, D. Subramanian
BMCBI
2005
189views more  BMCBI 2005»
14 years 11 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen
KES
2007
Springer
15 years 5 months ago
A Hybrid Symbolic-Statistical Approach to Modeling Metabolic Networks
Biological systems consist of many components and interactions between them. In Systems Biology the principal problem is modeling complex biological systems and reconstructing inte...
Marenglen Biba, Stefano Ferilli, Nicola Di Mauro, ...
RECOMB
2010
Springer
15 years 6 months ago
Incremental Signaling Pathway Modeling by Data Integration
Constructing quantitative dynamic models of signaling pathways is an important task for computational systems biology. Pathway model construction is often an inherently incremental...
Geoffrey Koh, David Hsu, P. S. Thiagarajan