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» Performance Analysis Framework for Layout Analysis Methods
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136
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BMCBI
2010
132views more  BMCBI 2010»
15 years 3 months ago
Parallel multiplicity and error discovery rate (EDR) in microarray experiments
Background: In microarray gene expression profiling experiments, differentially expressed genes (DEGs) are detected from among tens of thousands of genes on an array using statist...
Wayne Wenzhong Xu, Clay J. Carter
150
Voted
BMCBI
2005
169views more  BMCBI 2005»
15 years 3 months ago
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
Voichita D. Marinescu, Isaac S. Kohane, Alberto Ri...
124
Voted
BMCBI
2005
147views more  BMCBI 2005»
15 years 3 months ago
Calibration of mass spectrometric peptide mass fingerprint data without specific external or internal calibrants
Background: Peptide Mass Fingerprinting (PMF) is a widely used mass spectrometry (MS) method of analysis of proteins and peptides. It relies on the comparison between experimental...
Witold E. Wolski, Maciej Lalowski, Peter Jungblut,...
ICCAD
1997
IEEE
137views Hardware» more  ICCAD 1997»
15 years 7 months ago
Optimization techniques for high-performance digital circuits
The relentless push for high performance in custom digital circuits has led to renewed emphasis on circuit optimization or tuning. The parameters of the optimization are typically...
Chandramouli Visweswariah
155
Voted
BMCBI
2008
100views more  BMCBI 2008»
15 years 3 months ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....
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