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BMCBI
2005
133views more  BMCBI 2005»
14 years 9 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
TMI
2008
66views more  TMI 2008»
14 years 9 months ago
Feature Normalization via Expectation Maximization and Unsupervised Nonparametric Classification For M-FISH Chromosome Images
Multicolor fluorescence in situ hybridization (M-FISH) techniques provide color karyotyping that allows simultaneous analysis of numerical and structural abnormalities of whole hum...
Hyohoon Choi, Alan C. Bovik, Kenneth R. Castleman
BMCBI
2004
169views more  BMCBI 2004»
14 years 9 months ago
A power law global error model for the identification of differentially expressed genes in microarray data
Background: High-density oligonucleotide microarray technology enables the discovery of genes that are transcriptionally modulated in different biological samples due to physiolog...
Norman Pavelka, Mattia Pelizzola, Caterina Vizzard...
BMCBI
2010
150views more  BMCBI 2010»
14 years 9 months ago
DeltaProt: a software toolbox for comparative genomics
Background: Statistical bioinformatics is the study of biological data sets obtained by new micro-technologies by means of proper statistical methods. For a better understanding o...
Steinar Thorvaldsen, Tor Flå, Nils Willassen
NECO
2007
150views more  NECO 2007»
14 years 9 months ago
Reinforcement Learning, Spike-Time-Dependent Plasticity, and the BCM Rule
Learning agents, whether natural or artificial, must update their internal parameters in order to improve their behavior over time. In reinforcement learning, this plasticity is ...
Dorit Baras, Ron Meir