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BMCBI
2008
135views more  BMCBI 2008»
14 years 10 months ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...
BMCBI
2010
150views more  BMCBI 2010»
14 years 11 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
GECCO
2005
Springer
131views Optimization» more  GECCO 2005»
15 years 4 months ago
Multipopulation cooperative coevolutionary programming (MCCP) to enhance design innovation
This paper describes the development of an evolutionary algorithm called Multipopulation Cooperative Coevolutionary Programming (MCCP) that extends Genetic Programming (GP) to sea...
Emily M. Zechman, S. Ranji Ranjithan
NIPS
2007
15 years 4 days ago
Probabilistic Matrix Factorization
Many existing approaches to collaborative filtering can neither handle very large datasets nor easily deal with users who have very few ratings. In this paper we present the Prob...
Ruslan Salakhutdinov, Andriy Mnih
PAMI
2006
206views more  PAMI 2006»
14 years 10 months ago
MILES: Multiple-Instance Learning via Embedded Instance Selection
Multiple-instance problems arise from the situations where training class labels are attached to sets of samples (named bags), instead of individual samples within each bag (called...
Yixin Chen, Jinbo Bi, James Ze Wang