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BMCBI
2010
113views more  BMCBI 2010»
14 years 10 months ago
Class prediction for high-dimensional class-imbalanced data
Background: The goal of class prediction studies is to develop rules to accurately predict the class membership of new samples. The rules are derived using the values of the varia...
Rok Blagus, Lara Lusa
BMCBI
2008
71views more  BMCBI 2008»
14 years 10 months ago
Examining the significance of fingerprint-based classifiers
Background: Experimental examinations of biofluids to measure concentrations of proteins or their fragments or metabolites are being explored as a means of early disease detection...
Brian T. Luke, Jack R. Collins
BMCBI
2007
207views more  BMCBI 2007»
14 years 10 months ago
Discovering biomarkers from gene expression data for predicting cancer subgroups using neural networks and relational fuzzy clus
Background: The four heterogeneous childhood cancers, neuroblastoma, non-Hodgkin lymphoma, rhabdomyosarcoma, and Ewing sarcoma present a similar histology of small round blue cell...
Nikhil R. Pal, Kripamoy Aguan, Animesh Sharma, Shu...
BMCBI
2006
158views more  BMCBI 2006»
14 years 10 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
BMCBI
2007
217views more  BMCBI 2007»
14 years 10 months ago
On consensus biomarker selection
Background: Recent development of mass spectrometry technology enabled the analysis of complex peptide mixtures. A lot of effort is currently devoted to the identification of biom...
Janusz Dutkowski, Anna Gambin