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» Phylogenetic Comparative Assembly
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ISMB
2007
14 years 11 months ago
Automatic genome-wide reconstruction of phylogenetic gene trees
Gene duplication and divergence is a major evolutionary force. Despite the growing number of fully sequenced genomes, methods for investigating these events on a genome-wide scale...
Ilan Wapinski, Avi Pfeffer, Nir Friedman, Aviv Reg...
BMCBI
2010
104views more  BMCBI 2010»
14 years 9 months ago
A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-or
Background: G protein-coupled receptors (GPCRs) represent a family of well-characterized drug targets with significant therapeutic value. Phylogenetic classifications may help to ...
Eelke van der Horst, Julio E. Peironcely, Adriaan ...
BMCBI
2008
125views more  BMCBI 2008»
14 years 9 months ago
A fast algorithm for the multiple genome rearrangement problem with weighted reversals and transpositions
Background: Due to recent progress in genome sequencing, more and more data for phylogenetic reconstruction based on rearrangement distances between genomes become available. Howe...
Martin Bader, Mohamed Ibrahim Abouelhoda, Enno Ohl...
BMCBI
2005
118views more  BMCBI 2005»
14 years 9 months ago
Vestige: Maximum likelihood phylogenetic footprinting
Background: Phylogenetic footprinting is the identification of functional regions of DNA by their evolutionary conservation. This is achieved by comparing orthologous regions from...
Matthew J. Wakefield, Peter Maxwell, Gavin A. Hutt...
BMCBI
2004
123views more  BMCBI 2004»
14 years 9 months ago
galaxieEST: addressing EST identity through automated phylogenetic analysis
Background: Research involving expressed sequence tags (ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and sa...
R. Henrik Nilsson, Balaji Rajashekar, Karl-Henrik ...