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BMCBI
2007
131views more  BMCBI 2007»
13 years 6 months ago
An improved method for identifying functionally linked proteins using phylogenetic profiles
Background: Phylogenetic profiles record the occurrence of homologs of genes across fully sequenced organisms. Proteins with similar profiles are typically components of protein c...
Shawn Cokus, Sayaka Mizutani, Matteo Pellegrini
COCOON
2005
Springer
13 years 11 months ago
Perfect Sorting by Reversals
In computational biology, gene order data is often modelled as signed permutations. A classical problem in genome comparison is to detect conserved segments in a permutation, that ...
Marie-France Sagot, Eric Tannier
BMCBI
2004
150views more  BMCBI 2004»
13 years 6 months ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...
NAR
2007
115views more  NAR 2007»
13 years 5 months ago
PReMod: a database of genome-wide mammalian cis-regulatory module predictions
We describe PReMod, a new database of genomewide cis-regulatory module (CRM) predictions for both the human and the mouse genomes. The prediction algorithm, described previously i...
Vincent Ferretti, Christian Poitras, Dominique Ber...
BMCBI
2010
101views more  BMCBI 2010»
13 years 6 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...