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» Physical limits of inference
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112
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BMCBI
2010
148views more  BMCBI 2010»
15 years 1 months ago
Applying unmixing to gene expression data for tumor phylogeny inference
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
Russell Schwartz, Stanley Shackney
BMCBI
2010
150views more  BMCBI 2010»
15 years 1 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
BMCBI
2008
140views more  BMCBI 2008»
15 years 1 months ago
GORouter: an RDF model for providing semantic query and inference services for Gene Ontology and its associations
Background: The most renowned biological ontology, Gene Ontology (GO) is widely used for annotations of genes and gene products of different organisms. However, there are shortcom...
Qingwei Xu, Yixiang Shi, Qiang Lu, Guo-qing Zhang,...
141
Voted
EON
2003
15 years 3 months ago
Racer: A Core Inference Engine for the Semantic Web
In this paper we describe Racer, which can be considered as a core inference engine for the semantic web. The Racer inference server offers two APIs that are already used by at le...
Volker Haarslev, Ralf Möller
BMCBI
2004
114views more  BMCBI 2004»
15 years 1 months ago
Extending the mutual information measure to rank inferred literature relationships
Background: Within the peer-reviewed literature, associations between two things are not always recognized until commonalities between them become apparent. These commonalities ca...
Jonathan D. Wren