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BIODATAMINING
2008
147views more  BIODATAMINING 2008»
14 years 10 months ago
Neural networks for genetic epidemiology: past, present, and future
During the past two decades, the field of human genetics has experienced an information explosion. The completion of the human genome project and the development of high throughpu...
Alison A. Motsinger-Reif, Marylyn D. Ritchie
BMCBI
2010
169views more  BMCBI 2010»
14 years 10 months ago
eCOMPAGT integrates mtDNA: import, validation and export of mitochondrial DNA profiles for population genetics, tumour dynamics
Background: Mitochondrial DNA (mtDNA) is widely being used for population genetics, forensic DNA fingerprinting and clinical disease association studies. The recent past has uncov...
Hansi Weißensteiner, Sebastian Schönher...
BMCBI
2010
183views more  BMCBI 2010»
14 years 10 months ago
SOPRA: Scaffolding algorithm for paired reads via statistical optimization
Background: High throughput sequencing (HTS) platforms produce gigabases of short read (<100 bp) data per run. While these short reads are adequate for resequencing application...
Adel Dayarian, Todd P. Michael, Anirvan M. Sengupt...
BMCBI
2008
242views more  BMCBI 2008»
14 years 10 months ago
annot8r: GO, EC and KEGG annotation of EST datasets
Background: The expressed sequence tag (EST) methodology is an attractive option for the generation of sequence data for species for which no completely sequenced genome is availa...
Ralf Schmid, Mark L. Blaxter
BMCBI
2010
109views more  BMCBI 2010»
14 years 10 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...