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BMCBI
2008
244views more  BMCBI 2008»
14 years 11 months ago
RNAalifold: improved consensus structure prediction for RNA alignments
Background: The prediction of a consensus structure for a set of related RNAs is an important first step for subsequent analyses. RNAalifold, which computes the minimum energy str...
Stephan H. F. Bernhart, Ivo L. Hofacker, Sebastian...
BMCBI
2010
124views more  BMCBI 2010»
14 years 11 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
BMCBI
2008
115views more  BMCBI 2008»
14 years 11 months ago
Systems biology driven software design for the research enterprise
Background: In systems biology, and many other areas of research, there is a need for the interoperability of tools and data sources that were not originally designed to be integr...
John Boyle, Christopher C. Cavnor, Sarah A. Killco...
CORR
2008
Springer
121views Education» more  CORR 2008»
14 years 11 months ago
Rate-Distortion via Markov Chain Monte Carlo
We propose an approach to lossy source coding, utilizing ideas from Gibbs sampling, simulated annealing, and Markov Chain Monte Carlo (MCMC). The idea is to sample a reconstructio...
Shirin Jalali, Tsachy Weissman
AO
2006
127views more  AO 2006»
14 years 11 months ago
Formal ontology meets industry
in ontology is quite abstract and often based on toy-examples to the point that the gap between the work of theoreticians and the needs of real applications is too wide to be cross...
Stefano Borgo, Matteo Cristani, Roberta Cuel